Tissue adaptation rate in the treatment of Dupuytren contracture

Robert Bram Giesberts*, Anne Marjan ter Haar, Gerrit Martijn Sanderman, Edsko Evert Geert Hekman, Gijsbertus Jacob Verkerke

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    31 Downloads (Pure)

    Abstract

    Study Design: Basic research (cross-sectional). Introduction: Dupuytren disease can cause disabling contractures of the finger joints. After partial fasciectomy, postoperative hand splinting helps to maintain extension range of motion.

    Purpose of the Study: To measure how the contraction forces of the finger on the splint change over time. Methods: Subjects who were treated for Dupuytren contracture with partial fasciectomy were invited to participate in this study. Force sensors were placed in their dorsal extension splint, and the applied force was measured continually for several weeks.

    Results: Eleven subjects (aged 59-75 years) with the metacarpophalangeal (8) or proximal interphalangeal (3) as their most severely affected finger joint participated. Each night, the measured force consistently decreased to reach a plateau after about 3 hour (adaptation time, 2.55; 95% confidence interval, 0.2-31.8 hours). The time to reach this plateau decreased with time after surgery (≈5%/day, P =.0005, R 2 = 0.08).

    Discussion and Conclusions: The observed rate of decrease in the measured force indicates a tissue adaptation time of approximately 3 hours.

    Original languageEnglish
    JournalJournal of Hand Therapy
    DOIs
    Publication statusAccepted/In press - 27 Mar 2019

    Fingerprint

    Dupuytren Contracture
    Finger Joint
    Splints
    Contracture
    Articular Range of Motion
    Ambulatory Surgical Procedures
    Fingers
    Research Design
    Hand
    Confidence Intervals

    Keywords

    • Dupuytren
    • Force
    • Postoperative hand splinting
    • Tissue adaptation

    Cite this

    @article{87b43e9814a5433bb8adc112989c2419,
    title = "Tissue adaptation rate in the treatment of Dupuytren contracture",
    abstract = "Study Design: Basic research (cross-sectional). Introduction: Dupuytren disease can cause disabling contractures of the finger joints. After partial fasciectomy, postoperative hand splinting helps to maintain extension range of motion. Purpose of the Study: To measure how the contraction forces of the finger on the splint change over time. Methods: Subjects who were treated for Dupuytren contracture with partial fasciectomy were invited to participate in this study. Force sensors were placed in their dorsal extension splint, and the applied force was measured continually for several weeks.Results: Eleven subjects (aged 59-75 years) with the metacarpophalangeal (8) or proximal interphalangeal (3) as their most severely affected finger joint participated. Each night, the measured force consistently decreased to reach a plateau after about 3 hour (adaptation time, 2.55; 95{\%} confidence interval, 0.2-31.8 hours). The time to reach this plateau decreased with time after surgery (≈5{\%}/day, P =.0005, R 2 = 0.08).Discussion and Conclusions: The observed rate of decrease in the measured force indicates a tissue adaptation time of approximately 3 hours.",
    keywords = "Dupuytren, Force, Postoperative hand splinting, Tissue adaptation",
    author = "Giesberts, {Robert Bram} and {ter Haar}, {Anne Marjan} and Sanderman, {Gerrit Martijn} and Hekman, {Edsko Evert Geert} and Verkerke, {Gijsbertus Jacob}",
    year = "2019",
    month = "3",
    day = "27",
    doi = "10.1016/j.jht.2018.09.014",
    language = "English",
    journal = "Journal of Hand Therapy",
    issn = "0894-1130",
    publisher = "Hanley and Belfus Inc.",

    }

    Tissue adaptation rate in the treatment of Dupuytren contracture. / Giesberts, Robert Bram; ter Haar, Anne Marjan; Sanderman, Gerrit Martijn; Hekman, Edsko Evert Geert; Verkerke, Gijsbertus Jacob.

    In: Journal of Hand Therapy, 27.03.2019.

    Research output: Contribution to journalArticleAcademicpeer-review

    TY - JOUR

    T1 - Tissue adaptation rate in the treatment of Dupuytren contracture

    AU - Giesberts, Robert Bram

    AU - ter Haar, Anne Marjan

    AU - Sanderman, Gerrit Martijn

    AU - Hekman, Edsko Evert Geert

    AU - Verkerke, Gijsbertus Jacob

    PY - 2019/3/27

    Y1 - 2019/3/27

    N2 - Study Design: Basic research (cross-sectional). Introduction: Dupuytren disease can cause disabling contractures of the finger joints. After partial fasciectomy, postoperative hand splinting helps to maintain extension range of motion. Purpose of the Study: To measure how the contraction forces of the finger on the splint change over time. Methods: Subjects who were treated for Dupuytren contracture with partial fasciectomy were invited to participate in this study. Force sensors were placed in their dorsal extension splint, and the applied force was measured continually for several weeks.Results: Eleven subjects (aged 59-75 years) with the metacarpophalangeal (8) or proximal interphalangeal (3) as their most severely affected finger joint participated. Each night, the measured force consistently decreased to reach a plateau after about 3 hour (adaptation time, 2.55; 95% confidence interval, 0.2-31.8 hours). The time to reach this plateau decreased with time after surgery (≈5%/day, P =.0005, R 2 = 0.08).Discussion and Conclusions: The observed rate of decrease in the measured force indicates a tissue adaptation time of approximately 3 hours.

    AB - Study Design: Basic research (cross-sectional). Introduction: Dupuytren disease can cause disabling contractures of the finger joints. After partial fasciectomy, postoperative hand splinting helps to maintain extension range of motion. Purpose of the Study: To measure how the contraction forces of the finger on the splint change over time. Methods: Subjects who were treated for Dupuytren contracture with partial fasciectomy were invited to participate in this study. Force sensors were placed in their dorsal extension splint, and the applied force was measured continually for several weeks.Results: Eleven subjects (aged 59-75 years) with the metacarpophalangeal (8) or proximal interphalangeal (3) as their most severely affected finger joint participated. Each night, the measured force consistently decreased to reach a plateau after about 3 hour (adaptation time, 2.55; 95% confidence interval, 0.2-31.8 hours). The time to reach this plateau decreased with time after surgery (≈5%/day, P =.0005, R 2 = 0.08).Discussion and Conclusions: The observed rate of decrease in the measured force indicates a tissue adaptation time of approximately 3 hours.

    KW - Dupuytren

    KW - Force

    KW - Postoperative hand splinting

    KW - Tissue adaptation

    UR - http://www.scopus.com/inward/record.url?scp=85063262539&partnerID=8YFLogxK

    U2 - 10.1016/j.jht.2018.09.014

    DO - 10.1016/j.jht.2018.09.014

    M3 - Article

    AN - SCOPUS:85063262539

    JO - Journal of Hand Therapy

    JF - Journal of Hand Therapy

    SN - 0894-1130

    ER -