Efficient and selective electrical stimulation and recording of neural activity in peripheral, spinal, or central neural pathways require microelectrode arrays (MEAs) at micrometer of nanometer scale. At present, wire arrays in brain, flexible linear arrays in the cochlea, and cuff arrays around nerve trunks are in experimental and/or clinical use. Two- and three-dimensional brushlike microarrays and 'sieves', with around a hundred electrode sites, have been proposed, fabricated in microtechnology, and/or tested in a numer of laboratories. ...... In this chapter we report the latest progress regarding two aspects: (1) enhanced neurophilic/neurophobic contrast and (2) spontaneous and synchronized activity of patterned host islands.
|Title of host publication||Handbook of Neural Engineering|
|Place of Publication||U.S.A.|
|Number of pages||12|
|Publication status||Published - 2007|
|Name||IEEE Press Series in Biomedical Engineering|
|Publisher||John Wiley & Sons, Inc.|
- BSS-Neurotechnology and cellular engineering
Rutten, W., Ruardij, T. G., Marani, E., & Roelofsen, B. H. (2007). Towards a cultured neural probe: patterning of networks and their electrical activity. In M. Akay (Ed.), Handbook of Neural Engineering (pp. 357-368). (IEEE Press Series in Biomedical Engineering; No. 2). U.S.A.: Wiley.