Towards paper-based point of care affinity proteomics

Thiruppathiraja Chinnasamy, Loes I. Segerink, Mats Nystrand, Jesper Gantelius, Helene Andersson Svahn*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Affinity-based methods such as protein microarrays have come to complement conventional mass/charge-based techniques for proteomic characterization of biological samples. Simultaneous measurement of hundreds or even thousands of serum biomarkers such as antibodies, antigens and other proteins may greatly improve the diagnostic accuracy in a variety of conditions such as autoimmune disorders, infections and several cancers. However, today's technologies for affinity proteomics are cumbersome, require expensive equipment and skilled operators. Here, we present two novel paper-based techniques developed in our lab that aim to bridge the gap between highly multiplexed affinity proteomics and point of care testing.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherThe Chemical and Biological Microsystems Society
Pages64-66
Number of pages3
ISBN (Electronic)9780979806476
Publication statusPublished - 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2014 - Henry B. Gonzalez Convention Center, San Antonio, United States
Duration: 26 Oct 201430 Oct 2014
Conference number: 18

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2014
Abbreviated titleMicroTAS 2014
CountryUnited States
CitySan Antonio
Period26/10/1430/10/14

Keywords

  • Affinity proteomics
  • Gold nanoparticles
  • Paper
  • Point of care
  • Protein microarray

Fingerprint Dive into the research topics of 'Towards paper-based point of care affinity proteomics'. Together they form a unique fingerprint.

Cite this