Towards pH sensing in blood-vessel-on-a-chip

Esther  Tanumihardja; Wouter  Olthuis; Albert  van den Berg

Towards pH sensing in blood-vessel-on-a-chip

Esther Tanumihardja, Wouter Olthuis, Albert van den Berg

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Abstract

The Vascular Engineering on chip using differentiated Stem Cells (VESCEL) project aims to realize an on-chip model of human vasculature, where living cells are cultured and perfused in micrometer size compartments to mimic human vasculature function. This part of the VESCEL project aims to integrate micro sensors in the to-be-developed vasculature model, namely to monitor pH, PO2, and nitric oxide. Initial results of ruthenium oxide nanorods (RuOx) sensor fabrication and its pH sensing performance are presented. RuOx showed Nernstian response to pH range of 4.00 to 10.00. Future work and applications are also discussed.

Original language	English
Number of pages	1
Publication status	Published - 12 Dec 2017
Event	International MicroNanoConference, iMNC 2017 - Beurs van Berlage, Amsterdam, Netherlands Duration: 12 Dec 2017 → 13 Dec 2017

Conference

Conference	International MicroNanoConference, iMNC 2017
Abbreviated title	iMNC
Country/Territory	Netherlands
City	Amsterdam
Period	12/12/17 → 13/12/17

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iMNC poster 2017Final published version, 12.9 MB

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title = "Towards pH sensing in blood-vessel-on-a-chip",

abstract = "The Vascular Engineering on chip using differentiated Stem Cells (VESCEL) project aims to realize an on-chip model of human vasculature, where living cells are cultured and perfused in micrometer size compartments to mimic human vasculature function. This part of the VESCEL project aims to integrate micro sensors in the to-be-developed vasculature model, namely to monitor pH, PO2, and nitric oxide. Initial results of ruthenium oxide nanorods (RuOx) sensor fabrication and its pH sensing performance are presented. RuOx showed Nernstian response to pH range of 4.00 to 10.00. Future work and applications are also discussed.",

author = "Esther Tanumihardja and Wouter Olthuis and {van den Berg}, Albert",

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note = "International MicroNanoConference, iMNC 2017, iMNC ; Conference date: 12-12-2017 Through 13-12-2017",

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TY - CONF

T1 - Towards pH sensing in blood-vessel-on-a-chip

AU - Tanumihardja, Esther

AU - Olthuis, Wouter

AU - van den Berg, Albert

PY - 2017/12/12

Y1 - 2017/12/12

N2 - The Vascular Engineering on chip using differentiated Stem Cells (VESCEL) project aims to realize an on-chip model of human vasculature, where living cells are cultured and perfused in micrometer size compartments to mimic human vasculature function. This part of the VESCEL project aims to integrate micro sensors in the to-be-developed vasculature model, namely to monitor pH, PO2, and nitric oxide. Initial results of ruthenium oxide nanorods (RuOx) sensor fabrication and its pH sensing performance are presented. RuOx showed Nernstian response to pH range of 4.00 to 10.00. Future work and applications are also discussed.

AB - The Vascular Engineering on chip using differentiated Stem Cells (VESCEL) project aims to realize an on-chip model of human vasculature, where living cells are cultured and perfused in micrometer size compartments to mimic human vasculature function. This part of the VESCEL project aims to integrate micro sensors in the to-be-developed vasculature model, namely to monitor pH, PO2, and nitric oxide. Initial results of ruthenium oxide nanorods (RuOx) sensor fabrication and its pH sensing performance are presented. RuOx showed Nernstian response to pH range of 4.00 to 10.00. Future work and applications are also discussed.

M3 - Poster

T2 - International MicroNanoConference, iMNC 2017

Y2 - 12 December 2017 through 13 December 2017

ER -

Towards pH sensing in blood-vessel-on-a-chip

Abstract

Conference

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