Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device

I. van Uitert; Y. Cesa; Hans L. de Boer; Johan G. Bomer; Martin L. Bennink; Severine le Gac; Albert van den Berg

Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device

I. van Uitert, Y. Cesa, Hans L. de Boer, Johan G. Bomer, Martin L. Bennink, Severine le Gac, Albert van den Berg

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electri-cal characterization to optical investigation and that enable the preparation of asym-metrical membranes: a “macro��? device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.

Original language	Undefined
Title of host publication	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Editors	L.E. Locascio, M. Gaitan, B.M. Paegel, D.J. Ross, W.N. Vreeland
Place of Publication	San Diego
Publisher	The Chemical and Biological Microsystems Society
Pages	194-196
Number of pages	3
ISBN (Print)	978-0-9798064-1-4
Publication status	Published - 12 Oct 2008
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2008 - San Diego, United States Duration: 12 Oct 2008 → 16 Oct 2008 Conference number: 12

Publication series

Name	Micro Total Analysis Systems
Publisher	Chemical and Biological Micro Systems Society
Number	412
Volume	1
ISSN (Print)	1556-5890

Conference

Conference	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2008
Abbreviated title	MicroTAS
Country/Territory	United States
City	San Diego
Period	12/10/08 → 16/10/08

Keywords

BIOS-Micro/nanofluidics
Electrical properties
membrane composition
METIS-255464
IR-65349
BLMs
Asymmetry
EWI-14977

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Cite this

van Uitert, I., Cesa, Y., de Boer, H. L., Bomer, J. G., Bennink, M. L., le Gac, S., & van den Berg, A. (2008). Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. In L. E. Locascio, M. Gaitan, B. M. Paegel, D. J. Ross, & W. N. Vreeland (Eds.), 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 194-196). (Micro Total Analysis Systems; Vol. 1, No. 412). The Chemical and Biological Microsystems Society.

van Uitert, I. ; Cesa, Y. ; de Boer, Hans L. et al. / Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. editor / L.E. Locascio ; M. Gaitan ; B.M. Paegel ; D.J. Ross ; W.N. Vreeland. San Diego : The Chemical and Biological Microsystems Society, 2008. pp. 194-196 (Micro Total Analysis Systems; 412).

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title = "Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device",

abstract = "We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electri-cal characterization to optical investigation and that enable the preparation of asym-metrical membranes: a “macro��? device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.",

keywords = "BIOS-Micro/nanofluidics, Electrical properties, membrane composition, METIS-255464, IR-65349, BLMs, Asymmetry, EWI-14977",

author = "{van Uitert}, I. and Y. Cesa and {de Boer}, {Hans L.} and Bomer, {Johan G.} and Bennink, {Martin L.} and {le Gac}, Severine and {van den Berg}, Albert",

year = "2008",

month = oct,

day = "12",

language = "Undefined",

isbn = "978-0-9798064-1-4",

series = "Micro Total Analysis Systems",

publisher = "The Chemical and Biological Microsystems Society",

number = "412",

pages = "194--196",

editor = "L.E. Locascio and M. Gaitan and B.M. Paegel and D.J. Ross and W.N. Vreeland",

booktitle = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

note = "null ; Conference date: 12-10-2008 Through 16-10-2008",

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van Uitert, I, Cesa, Y, de Boer, HL, Bomer, JG , Bennink, ML , le Gac, S & van den Berg, A 2008, Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. in LE Locascio, M Gaitan, BM Paegel, DJ Ross & WN Vreeland (eds), 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Micro Total Analysis Systems, no. 412, vol. 1, The Chemical and Biological Microsystems Society, San Diego, pp. 194-196, 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2008, San Diego, California, United States, 12/10/08.

Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. / van Uitert, I.; Cesa, Y.; de Boer, Hans L. et al.

12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. ed. / L.E. Locascio; M. Gaitan; B.M. Paegel; D.J. Ross; W.N. Vreeland. San Diego : The Chemical and Biological Microsystems Society, 2008. p. 194-196 (Micro Total Analysis Systems; Vol. 1, No. 412).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device

AU - van Uitert, I.

AU - Cesa, Y.

AU - de Boer, Hans L.

AU - Bomer, Johan G.

AU - Bennink, Martin L.

AU - le Gac, Severine

AU - van den Berg, Albert

N1 - Conference code: 12

PY - 2008/10/12

Y1 - 2008/10/12

N2 - We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electri-cal characterization to optical investigation and that enable the preparation of asym-metrical membranes: a “macro��? device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.

AB - We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electri-cal characterization to optical investigation and that enable the preparation of asym-metrical membranes: a “macro��? device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.

KW - BIOS-Micro/nanofluidics

KW - Electrical properties

KW - membrane composition

KW - METIS-255464

KW - IR-65349

KW - BLMs

KW - Asymmetry

KW - EWI-14977

M3 - Conference contribution

SN - 978-0-9798064-1-4

T3 - Micro Total Analysis Systems

SP - 194

EP - 196

BT - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences

A2 - Locascio, L.E.

A2 - Gaitan, M.

A2 - Paegel, B.M.

A2 - Ross, D.J.

A2 - Vreeland, W.N.

PB - The Chemical and Biological Microsystems Society

CY - San Diego

Y2 - 12 October 2008 through 16 October 2008

ER -

van Uitert I, Cesa Y, de Boer HL, Bomer JG , Bennink ML , le Gac S et al. Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. In Locascio LE, Gaitan M, Paegel BM, Ross DJ, Vreeland WN, editors, 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. San Diego: The Chemical and Biological Microsystems Society. 2008. p. 194-196. (Micro Total Analysis Systems; 412).