Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device

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Abstract

We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electri-cal characterization to optical investigation and that enable the preparation of asym-metrical membranes: a “macro��? device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.
Original languageUndefined
Title of host publication12th International Conference on Miniaturized Systems for Chemistry and Life Sciences
EditorsL.E. Locascio, M. Gaitan, B.M. Paegel, D.J. Ross, W.N. Vreeland
Place of PublicationSan Diego
PublisherChemical and Biological Micro Systems Society
Pages194-196
Number of pages3
ISBN (Print)978-0-9798064-1-4
Publication statusPublished - 12 Oct 2008
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2008 - San Diego, United States
Duration: 12 Oct 200816 Oct 2008
Conference number: 12

Publication series

NameMicro Total Analysis Systems
PublisherChemical and Biological Micro Systems Society
Number412
Volume1
ISSN (Print)1556-5890

Conference

Conference12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2008
Abbreviated titleMicroTAS
CountryUnited States
CitySan Diego
Period12/10/0816/10/08

Keywords

  • BIOS-Micro/nanofluidics
  • Electrical properties
  • membrane composition
  • METIS-255464
  • IR-65349
  • BLMs
  • Asymmetry
  • EWI-14977

Cite this

van Uitert, I., Cesa, Y., de Boer, H. L., Bomer, J. G., Bennink, M. L., le Gac, S., & van den Berg, A. (2008). Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. In L. E. Locascio, M. Gaitan, B. M. Paegel, D. J. Ross, & W. N. Vreeland (Eds.), 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 194-196). (Micro Total Analysis Systems; Vol. 1, No. 412). San Diego: Chemical and Biological Micro Systems Society.
van Uitert, I. ; Cesa, Y. ; de Boer, Hans L. ; Bomer, Johan G. ; Bennink, Martin L. ; le Gac, Severine ; van den Berg, Albert. / Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. editor / L.E. Locascio ; M. Gaitan ; B.M. Paegel ; D.J. Ross ; W.N. Vreeland. San Diego : Chemical and Biological Micro Systems Society, 2008. pp. 194-196 (Micro Total Analysis Systems; 412).
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title = "Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device",
abstract = "We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electri-cal characterization to optical investigation and that enable the preparation of asym-metrical membranes: a “macro��? device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.",
keywords = "BIOS-Micro/nanofluidics, Electrical properties, membrane composition, METIS-255464, IR-65349, BLMs, Asymmetry, EWI-14977",
author = "{van Uitert}, I. and Y. Cesa and {de Boer}, {Hans L.} and Bomer, {Johan G.} and Bennink, {Martin L.} and {le Gac}, Severine and {van den Berg}, Albert",
year = "2008",
month = "10",
day = "12",
language = "Undefined",
isbn = "978-0-9798064-1-4",
series = "Micro Total Analysis Systems",
publisher = "Chemical and Biological Micro Systems Society",
number = "412",
pages = "194--196",
editor = "L.E. Locascio and M. Gaitan and B.M. Paegel and D.J. Ross and W.N. Vreeland",
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van Uitert, I, Cesa, Y, de Boer, HL, Bomer, JG, Bennink, ML, le Gac, S & van den Berg, A 2008, Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. in LE Locascio, M Gaitan, BM Paegel, DJ Ross & WN Vreeland (eds), 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Micro Total Analysis Systems, no. 412, vol. 1, Chemical and Biological Micro Systems Society, San Diego, pp. 194-196, 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2008, San Diego, United States, 12/10/08.

Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. / van Uitert, I.; Cesa, Y.; de Boer, Hans L.; Bomer, Johan G.; Bennink, Martin L.; le Gac, Severine; van den Berg, Albert.

12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. ed. / L.E. Locascio; M. Gaitan; B.M. Paegel; D.J. Ross; W.N. Vreeland. San Diego : Chemical and Biological Micro Systems Society, 2008. p. 194-196 (Micro Total Analysis Systems; Vol. 1, No. 412).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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T1 - Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device

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AU - Cesa, Y.

AU - de Boer, Hans L.

AU - Bomer, Johan G.

AU - Bennink, Martin L.

AU - le Gac, Severine

AU - van den Berg, Albert

PY - 2008/10/12

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N2 - We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electri-cal characterization to optical investigation and that enable the preparation of asym-metrical membranes: a “macro��? device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.

AB - We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electri-cal characterization to optical investigation and that enable the preparation of asym-metrical membranes: a “macro��? device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.

KW - BIOS-Micro/nanofluidics

KW - Electrical properties

KW - membrane composition

KW - METIS-255464

KW - IR-65349

KW - BLMs

KW - Asymmetry

KW - EWI-14977

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SN - 978-0-9798064-1-4

T3 - Micro Total Analysis Systems

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BT - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences

A2 - Locascio, L.E.

A2 - Gaitan, M.

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A2 - Ross, D.J.

A2 - Vreeland, W.N.

PB - Chemical and Biological Micro Systems Society

CY - San Diego

ER -

van Uitert I, Cesa Y, de Boer HL, Bomer JG, Bennink ML, le Gac S et al. Towards simultaneous electrical and optical investigation of BLMS using a novel microfluidic device. In Locascio LE, Gaitan M, Paegel BM, Ross DJ, Vreeland WN, editors, 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. San Diego: Chemical and Biological Micro Systems Society. 2008. p. 194-196. (Micro Total Analysis Systems; 412).