Towards the Use of Neuromusculoskeletal Modeling in Clinical Practice: A Feasibility Study in Parkinson Disease Patients

M. Romanato*, D. Volpe, A. Guiotto, F. Spolaor, M. Sartori, Z. Sawacha*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

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Electromyography (EMG)-driven neuromusculo-skeletal models (NMSM) are currently used to estimate joint moments and muscle forces during dynamic movements considering subject-specific neural-excitation patterns provided by the EMG data. However, these models are rarely adopted in routine clinical applications. This is partly due to limitations in obtaining realistic maxima voluntary contractions (MVC) in pathological subjects for calibration purposes and in the number of required experimental EMG signals that are difficult to be assessed in neurological conditions (e.g. Parkinson’s Disease (PD)). This study aims at verifying the feasibility of introducing EMG-driven NMSM for planning rehabilitation treatments in PD. Thus, a minimal experimental setup compatible with clinics requirements is proposed herein. Four different NMSM were implemented with two different EMG normalization methods and with two different set of experimental EMGs for the muscletendon unit mapping. Results seems promising as no statistically significant differences between the full model and the proposed reduced model were observed.

Original languageEnglish
Title of host publicationConverging Clinical and Engineering Research on Neurorehabilitation IV
Subtitle of host publicationProceedings of the 5th International Conference on Neurorehabilitation (ICNR2020), October 13–16, 2020
EditorsDiego Torricelli, Metin Akay, Jose L. Pons
PublisherSpringer Science + Business Media
Number of pages5
ISBN (Electronic)978-3-030-70316-5
ISBN (Print)978-3-030-70315-8, 978-3-030-70318-9
Publication statusPublished - 2022
Event5th International Conference on NeuroRehabilitation, ICNR 2020 - Virtual Event
Duration: 13 Oct 202016 Oct 2020
Conference number: 5

Publication series

NameBiosystems and Biorobotics
ISSN (Print)2195-3562
ISSN (Electronic)2195-3570


Conference5th International Conference on NeuroRehabilitation, ICNR 2020
Abbreviated titleICNR 2020
CityVirtual Event


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