Tractography demonstrates dentate-rubro-thalamic tract disruption in an adult with cerebellar mutism

K. van Baarsen, M. Kleinnijenhuis, T. Konert, Anne-Marie van Cappellen van Walsum, A. Grotenhuis

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)

Abstract

A 55-year-old female is presented with transient cerebellar mutism caused by a well-circumscribed left pontine infarction due to postoperative basilar perforator occlusion. Although conventional T2 imaging shows a well-demarcated lesion confined to the pontine region, diffusion tensor imaging shows an asymmetry in fractional anisotropy in the superior cerebellar peduncle. This supports the general hypothesis that cerebellar mutism is caused by functional disruption of the dentate-rubro-thalamic tract. Correlating postoperative anatomic changes to a heterogenic clinical syndrome remains challenging, however.
Original languageEnglish
Pages (from-to)617-622
Number of pages6
JournalCerebellum
Volume12
Issue number5
DOIs
Publication statusPublished - 2013

Keywords

  • METIS-296566
  • IR-86172

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