Transdermal timolol delivery from a Pluronic gel

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Abstract

In this work, the transdermal timolol (TM) delivery from a Pluronic F127 (PL) gel reservoir was investigated. Both gel concentration and the artificial membrane are used to regulate the TM delivery through pig stratum corneum (SC). At low PL concentrations and for high pore size membranes, the SC mainly controls the TM delivery. At high PL concentrations and for low pore size membranes, the contribution of the system (gel + artificial membrane) to the TM delivery becomes significant.
Original languageUndefined
Pages (from-to)e53-e55
JournalJournal of controlled release
Volume116
Issue number2
DOIs
Publication statusPublished - 2006

Keywords

  • METIS-235182
  • IR-71635

Cite this

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title = "Transdermal timolol delivery from a Pluronic gel",
abstract = "In this work, the transdermal timolol (TM) delivery from a Pluronic F127 (PL) gel reservoir was investigated. Both gel concentration and the artificial membrane are used to regulate the TM delivery through pig stratum corneum (SC). At low PL concentrations and for high pore size membranes, the SC mainly controls the TM delivery. At high PL concentrations and for low pore size membranes, the contribution of the system (gel + artificial membrane) to the TM delivery becomes significant.",
keywords = "METIS-235182, IR-71635",
author = "Dimitrios Stamatialis and Rolevink, {Hendrikus H.M.} and G.H. Koops",
note = "Proceedings of the Ninth European Symposium on Controlled Drug Delivery",
year = "2006",
doi = "10.1016/j.jconrel.2006.09.046",
language = "Undefined",
volume = "116",
pages = "e53--e55",
journal = "Journal of controlled release",
issn = "0168-3659",
publisher = "Elsevier",
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Transdermal timolol delivery from a Pluronic gel. / Stamatialis, Dimitrios; Rolevink, Hendrikus H.M.; Koops, G.H.

In: Journal of controlled release, Vol. 116, No. 2, 2006, p. e53-e55.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Transdermal timolol delivery from a Pluronic gel

AU - Stamatialis, Dimitrios

AU - Rolevink, Hendrikus H.M.

AU - Koops, G.H.

N1 - Proceedings of the Ninth European Symposium on Controlled Drug Delivery

PY - 2006

Y1 - 2006

N2 - In this work, the transdermal timolol (TM) delivery from a Pluronic F127 (PL) gel reservoir was investigated. Both gel concentration and the artificial membrane are used to regulate the TM delivery through pig stratum corneum (SC). At low PL concentrations and for high pore size membranes, the SC mainly controls the TM delivery. At high PL concentrations and for low pore size membranes, the contribution of the system (gel + artificial membrane) to the TM delivery becomes significant.

AB - In this work, the transdermal timolol (TM) delivery from a Pluronic F127 (PL) gel reservoir was investigated. Both gel concentration and the artificial membrane are used to regulate the TM delivery through pig stratum corneum (SC). At low PL concentrations and for high pore size membranes, the SC mainly controls the TM delivery. At high PL concentrations and for low pore size membranes, the contribution of the system (gel + artificial membrane) to the TM delivery becomes significant.

KW - METIS-235182

KW - IR-71635

U2 - 10.1016/j.jconrel.2006.09.046

DO - 10.1016/j.jconrel.2006.09.046

M3 - Article

VL - 116

SP - e53-e55

JO - Journal of controlled release

JF - Journal of controlled release

SN - 0168-3659

IS - 2

ER -