Transdermal timolol delivery from a Pluronic gel

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Abstract

In this work, the transdermal timolol (TM) delivery from a Pluronic F127 (PL) gel reservoir was investigated. Both gel concentration and the artificial membrane are used to regulate the TM delivery through pig stratum corneum (SC). At low PL concentrations and for high pore size membranes, the SC mainly controls the TM delivery. At high PL concentrations and for low pore size membranes, the contribution of the system (gel + artificial membrane) to the TM delivery becomes significant.
Original languageUndefined
Pages (from-to)e53-e55
JournalJournal of controlled release
Volume116
Issue number2
DOIs
Publication statusPublished - 2006

Keywords

  • METIS-235182
  • IR-71635

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