Abstract
In contrast with entangled actin solutions, transiently cross-linked actin networks can provide highly elastic properties while still allowing for local rearrangements in the microstructure-on biological relevant time scales. Here, we show that thermal unbinding of transient cross-links entails local stress relaxation and energy dissipation in an intermediate elasticity dominated frequency regime. We quantify the viscoelastic response of an isotropically cross-linked actin network by experimentally tuning the off rate of the transiently cross-linking molecules, their density, and the solvent viscosity. We reproduce the measured frequency response by a semiphenomenological model that is predicated on microscopic unbinding events.
Original language | Undefined |
---|---|
Pages (from-to) | 108101-1-108101-4 |
Number of pages | 5 |
Journal | Physical review letters |
Volume | 101 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2008 |
Keywords
- IR-59955
- METIS-250787