Abstract
| Original language | Undefined |
|---|---|
| Pages (from-to) | 108101-1-108101-4 |
| Number of pages | 5 |
| Journal | Physical review letters |
| Volume | 101 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2008 |
Keywords
- IR-59955
- METIS-250787
Cite this
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Transient Binding and Dissipation in Cross-Linked Actin Networks. / Lieleg, O.; Claessens, Mireille Maria Anna Elisabeth; Luan, Y.; Bausch, A.R.
In: Physical review letters, Vol. 101, No. 10, 2008, p. 108101-1-108101-4.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Transient Binding and Dissipation in Cross-Linked Actin Networks
AU - Lieleg, O.
AU - Claessens, Mireille Maria Anna Elisabeth
AU - Luan, Y.
AU - Bausch, A.R.
PY - 2008
Y1 - 2008
N2 - In contrast with entangled actin solutions, transiently cross-linked actin networks can provide highly elastic properties while still allowing for local rearrangements in the microstructure-on biological relevant time scales. Here, we show that thermal unbinding of transient cross-links entails local stress relaxation and energy dissipation in an intermediate elasticity dominated frequency regime. We quantify the viscoelastic response of an isotropically cross-linked actin network by experimentally tuning the off rate of the transiently cross-linking molecules, their density, and the solvent viscosity. We reproduce the measured frequency response by a semiphenomenological model that is predicated on microscopic unbinding events.
AB - In contrast with entangled actin solutions, transiently cross-linked actin networks can provide highly elastic properties while still allowing for local rearrangements in the microstructure-on biological relevant time scales. Here, we show that thermal unbinding of transient cross-links entails local stress relaxation and energy dissipation in an intermediate elasticity dominated frequency regime. We quantify the viscoelastic response of an isotropically cross-linked actin network by experimentally tuning the off rate of the transiently cross-linking molecules, their density, and the solvent viscosity. We reproduce the measured frequency response by a semiphenomenological model that is predicated on microscopic unbinding events.
KW - IR-59955
KW - METIS-250787
U2 - 10.1103/PhysRevLett.101.108101
DO - 10.1103/PhysRevLett.101.108101
M3 - Article
VL - 101
SP - 108101-1-108101-4
JO - Physical review letters
JF - Physical review letters
SN - 0031-9007
IS - 10
ER -