Trapping cortical rat neurons

Tjitske Heida; Wim Rutten; Enrico Marani

doi:10.1109/IEMBS.2000.897974

Trapping cortical rat neurons

Tjitske Heida, Wim Rutten, Enrico Marani

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

Cortical rat neurons were trapped by dielectrophoresis (DEP). Experimental data were compared with theoretically deduced relationships. The neuron was represented by a single-shell model. A planar quadrupole electrode structure was used for the creation of a nonuniform field. The electrode structure was modeled as four point charges. The experimental data did almost completely fit the theoretical yield/time relationship. The theoretical yield/amplitude relationship, however, did only apply for a restricted amount of frequencies. The experimental frequency behaviour (i.e., the DEP-spectrum) did not apply to the theory. A difference in neuronal physiological state can produce different DEP-spectra. For two frequencies (10 kHz and 14 MHz) adhesion to the substrate and outgrowth of the neurons was investigated

Original language	Undefined
Title of host publication	Proceedings 2000 World Congress on Medical Physics and Biomedical Engineering
Place of Publication	Chicago, USA
Publisher	IEEE
Pages	-
Number of pages	4
ISBN (Print)	0-7803-6468-6 C
DOIs	https://doi.org/10.1109/IEMBS.2000.897974
Publication status	Published - 23 Jul 2000
Event	22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2000 - Chicago, United States Duration: 23 Jul 2000 → 28 Jul 2000 Conference number: 22

Publication series

Name
Publisher	IEEE
Volume	2

Conference

Conference	22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2000
Abbreviated title	EMBC
Country/Territory	United States
City	Chicago
Period	23/07/00 → 28/07/00

Keywords

METIS-114037
IR-17142

Access to Document

10.1109/IEMBS.2000.897974

00897974

Cite this

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title = "Trapping cortical rat neurons",

abstract = "Cortical rat neurons were trapped by dielectrophoresis (DEP). Experimental data were compared with theoretically deduced relationships. The neuron was represented by a single-shell model. A planar quadrupole electrode structure was used for the creation of a nonuniform field. The electrode structure was modeled as four point charges. The experimental data did almost completely fit the theoretical yield/time relationship. The theoretical yield/amplitude relationship, however, did only apply for a restricted amount of frequencies. The experimental frequency behaviour (i.e., the DEP-spectrum) did not apply to the theory. A difference in neuronal physiological state can produce different DEP-spectra. For two frequencies (10 kHz and 14 MHz) adhesion to the substrate and outgrowth of the neurons was investigated",

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T1 - Trapping cortical rat neurons

AU - Heida, Tjitske

AU - Rutten, Wim

AU - Marani, Enrico

N1 - Conference code: 22

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Y1 - 2000/7/23

N2 - Cortical rat neurons were trapped by dielectrophoresis (DEP). Experimental data were compared with theoretically deduced relationships. The neuron was represented by a single-shell model. A planar quadrupole electrode structure was used for the creation of a nonuniform field. The electrode structure was modeled as four point charges. The experimental data did almost completely fit the theoretical yield/time relationship. The theoretical yield/amplitude relationship, however, did only apply for a restricted amount of frequencies. The experimental frequency behaviour (i.e., the DEP-spectrum) did not apply to the theory. A difference in neuronal physiological state can produce different DEP-spectra. For two frequencies (10 kHz and 14 MHz) adhesion to the substrate and outgrowth of the neurons was investigated

AB - Cortical rat neurons were trapped by dielectrophoresis (DEP). Experimental data were compared with theoretically deduced relationships. The neuron was represented by a single-shell model. A planar quadrupole electrode structure was used for the creation of a nonuniform field. The electrode structure was modeled as four point charges. The experimental data did almost completely fit the theoretical yield/time relationship. The theoretical yield/amplitude relationship, however, did only apply for a restricted amount of frequencies. The experimental frequency behaviour (i.e., the DEP-spectrum) did not apply to the theory. A difference in neuronal physiological state can produce different DEP-spectra. For two frequencies (10 kHz and 14 MHz) adhesion to the substrate and outgrowth of the neurons was investigated

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DO - 10.1109/IEMBS.2000.897974

M3 - Conference contribution

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BT - Proceedings 2000 World Congress on Medical Physics and Biomedical Engineering

PB - IEEE

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