Abstract
Magnetic manipulation of particles in microfluidic systems has been applied only recently. Magnetic forces can be used for transport, positioning, separation and sorting of magnetic particles and magnetically tagged cells and eg proteins. Most commonly magnetic nanoparticles in microfluidics serve as a surface for bio- or
immunoassays, which can therefore be done in a small volume and very localised [1]. In this study magnetic trapping of commonly used spherical super paramagnetic particles (Endorem®) and elongated nanoparticles, Fe filled multi walled carbon nanotubes (Fe-MWNTs) is studied. Suspensions of both types of particles are in a
microfluidic chip and trapping is achieved by the use of a magnetic needle with a high gradient magnetic field (7500 T/m). Although the mass magnetization of the SPIO particles is a factor five higher compared to the Fe-MWNTs (figure 1) due to the low filling grade of the nanotubes trapping is still possible (figure 2). Furthermore
Fe-MWNTs have potential in lab-on-a-chip-devices thanks to there large surface area for binding of proteins etc.
immunoassays, which can therefore be done in a small volume and very localised [1]. In this study magnetic trapping of commonly used spherical super paramagnetic particles (Endorem®) and elongated nanoparticles, Fe filled multi walled carbon nanotubes (Fe-MWNTs) is studied. Suspensions of both types of particles are in a
microfluidic chip and trapping is achieved by the use of a magnetic needle with a high gradient magnetic field (7500 T/m). Although the mass magnetization of the SPIO particles is a factor five higher compared to the Fe-MWNTs (figure 1) due to the low filling grade of the nanotubes trapping is still possible (figure 2). Furthermore
Fe-MWNTs have potential in lab-on-a-chip-devices thanks to there large surface area for binding of proteins etc.
| Original language | English |
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| Number of pages | 1 |
| Publication status | Published - 25 May 2010 |
| Event | 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers 2010 - Rostock, Germany Duration: 25 May 2010 → 29 May 2010 |
Conference
| Conference | 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers 2010 |
|---|---|
| Country/Territory | Germany |
| City | Rostock |
| Period | 25/05/10 → 29/05/10 |