Tunable and processable shape memory composites based on degradable polymers

Xi Zhang, Mike A. Geven, Dirk W. Grijpma, Ton Peijs, Julien E. Gautrot

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Abstract

Biodegradable shape memory polymers are attractive materials for the design of biomedical scaffolds as they allow deploying implants remotely with minimal intervention, whilst allowing degradation and tissue repair. However, shape memory properties are difficult to design from common degradable polymers, without chemical modifications. Here were developed readily tunable processable shape memory polymer composites (SMPCs) based on established degradable polymers in the biomedical field (poly(trimethylene carbonate) (PTMC) and poly(lactic acid) (PLA) fibres). These SMPCs rely on the glass-rubber transition of the PLA network to trigger shape recovery, whilst the elastic PTMC matrix optimises the full recovery of the scaffold to permanent shape. We demonstrate the performance of SMPCs can be readily designed by adjusting the loading and processing of the fibre network, or through the addition of plasticizing poly(ethylene glycol) chains. Importantly, we demonstrate that the use of cut fibres allows the solution processing of SMPCs, which should enable the design of potentially degradable shape memory 3D scaffolds with complex shapes.

Original languageEnglish
Pages (from-to)323-331
Number of pages9
JournalPolymer
Volume122
DOIs
Publication statusPublished - 28 Jul 2017

Fingerprint

Shape memory effect
Polymers
Composite materials
Scaffolds
Lactic acid
Fibers
Carbonates
Recovery
Rubber
Chemical modification
Processing
Polyethylene glycols
Repair
Tissue
Degradation
Glass

Keywords

  • Composites
  • Electrospun fibres
  • Shape memory polymers

Cite this

Zhang, Xi ; Geven, Mike A. ; Grijpma, Dirk W. ; Peijs, Ton ; Gautrot, Julien E. / Tunable and processable shape memory composites based on degradable polymers. In: Polymer. 2017 ; Vol. 122. pp. 323-331.
@article{7b4c5167d65b41339c36202218500f29,
title = "Tunable and processable shape memory composites based on degradable polymers",
abstract = "Biodegradable shape memory polymers are attractive materials for the design of biomedical scaffolds as they allow deploying implants remotely with minimal intervention, whilst allowing degradation and tissue repair. However, shape memory properties are difficult to design from common degradable polymers, without chemical modifications. Here were developed readily tunable processable shape memory polymer composites (SMPCs) based on established degradable polymers in the biomedical field (poly(trimethylene carbonate) (PTMC) and poly(lactic acid) (PLA) fibres). These SMPCs rely on the glass-rubber transition of the PLA network to trigger shape recovery, whilst the elastic PTMC matrix optimises the full recovery of the scaffold to permanent shape. We demonstrate the performance of SMPCs can be readily designed by adjusting the loading and processing of the fibre network, or through the addition of plasticizing poly(ethylene glycol) chains. Importantly, we demonstrate that the use of cut fibres allows the solution processing of SMPCs, which should enable the design of potentially degradable shape memory 3D scaffolds with complex shapes.",
keywords = "Composites, Electrospun fibres, Shape memory polymers",
author = "Xi Zhang and Geven, {Mike A.} and Grijpma, {Dirk W.} and Ton Peijs and Gautrot, {Julien E.}",
year = "2017",
month = "7",
day = "28",
doi = "10.1016/j.polymer.2017.06.066",
language = "English",
volume = "122",
pages = "323--331",
journal = "Polymer",
issn = "0032-3861",
publisher = "Elsevier",

}

Tunable and processable shape memory composites based on degradable polymers. / Zhang, Xi; Geven, Mike A.; Grijpma, Dirk W.; Peijs, Ton; Gautrot, Julien E.

In: Polymer, Vol. 122, 28.07.2017, p. 323-331.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Tunable and processable shape memory composites based on degradable polymers

AU - Zhang, Xi

AU - Geven, Mike A.

AU - Grijpma, Dirk W.

AU - Peijs, Ton

AU - Gautrot, Julien E.

PY - 2017/7/28

Y1 - 2017/7/28

N2 - Biodegradable shape memory polymers are attractive materials for the design of biomedical scaffolds as they allow deploying implants remotely with minimal intervention, whilst allowing degradation and tissue repair. However, shape memory properties are difficult to design from common degradable polymers, without chemical modifications. Here were developed readily tunable processable shape memory polymer composites (SMPCs) based on established degradable polymers in the biomedical field (poly(trimethylene carbonate) (PTMC) and poly(lactic acid) (PLA) fibres). These SMPCs rely on the glass-rubber transition of the PLA network to trigger shape recovery, whilst the elastic PTMC matrix optimises the full recovery of the scaffold to permanent shape. We demonstrate the performance of SMPCs can be readily designed by adjusting the loading and processing of the fibre network, or through the addition of plasticizing poly(ethylene glycol) chains. Importantly, we demonstrate that the use of cut fibres allows the solution processing of SMPCs, which should enable the design of potentially degradable shape memory 3D scaffolds with complex shapes.

AB - Biodegradable shape memory polymers are attractive materials for the design of biomedical scaffolds as they allow deploying implants remotely with minimal intervention, whilst allowing degradation and tissue repair. However, shape memory properties are difficult to design from common degradable polymers, without chemical modifications. Here were developed readily tunable processable shape memory polymer composites (SMPCs) based on established degradable polymers in the biomedical field (poly(trimethylene carbonate) (PTMC) and poly(lactic acid) (PLA) fibres). These SMPCs rely on the glass-rubber transition of the PLA network to trigger shape recovery, whilst the elastic PTMC matrix optimises the full recovery of the scaffold to permanent shape. We demonstrate the performance of SMPCs can be readily designed by adjusting the loading and processing of the fibre network, or through the addition of plasticizing poly(ethylene glycol) chains. Importantly, we demonstrate that the use of cut fibres allows the solution processing of SMPCs, which should enable the design of potentially degradable shape memory 3D scaffolds with complex shapes.

KW - Composites

KW - Electrospun fibres

KW - Shape memory polymers

UR - http://www.scopus.com/inward/record.url?scp=85021679901&partnerID=8YFLogxK

U2 - 10.1016/j.polymer.2017.06.066

DO - 10.1016/j.polymer.2017.06.066

M3 - Article

VL - 122

SP - 323

EP - 331

JO - Polymer

JF - Polymer

SN - 0032-3861

ER -