TY - JOUR
T1 - Twenty-four hour tonometry in patients suspected of chronic gastrointestinal ischemia
AU - Mensink, Peter B.F.
AU - Geelkerken, Robert H.
AU - Huisman, Ad B.
AU - Kuipers, Ernst J.
AU - Kolkman, Jeroen J.
PY - 2008/1/1
Y1 - 2008/1/1
N2 - Background and aims: Gastrointestinal tonometry is currently the only clinical diagnostic test that enables identification of symptomatic chronic gastrointestinal ischemia. Gastric exercise tonometry has proven its value for detection of ischemia in this patients group, but has its disadvantages. Earlier studies with postprandial tonometry gave unreliable results. In this study we challenged (again) the use of postprandial tonometry in patients suspected of gastrointestinal ischemia. Methods: Patients suspected for chronic gastrointestinal ischemia had standard diagnostic work up, including gastric exercise tonometry and 24-h tonometry using standard meals. Results: Thirty-three patients were enrolled in the study. Chronic gastrointestinal ischemia was diagnosed in 17 (52%) patients. The 24-h tonometry correctly predicted the presence of ischemia in 13/17 patients, and absence of ischemia in 15/16 patients. Conclusions: The use of 24-h tonometry after meals in patients suspected of gastrointestinal ischemia seems feasible, with promising accuracy for the detection of ischemia.
AB - Background and aims: Gastrointestinal tonometry is currently the only clinical diagnostic test that enables identification of symptomatic chronic gastrointestinal ischemia. Gastric exercise tonometry has proven its value for detection of ischemia in this patients group, but has its disadvantages. Earlier studies with postprandial tonometry gave unreliable results. In this study we challenged (again) the use of postprandial tonometry in patients suspected of gastrointestinal ischemia. Methods: Patients suspected for chronic gastrointestinal ischemia had standard diagnostic work up, including gastric exercise tonometry and 24-h tonometry using standard meals. Results: Thirty-three patients were enrolled in the study. Chronic gastrointestinal ischemia was diagnosed in 17 (52%) patients. The 24-h tonometry correctly predicted the presence of ischemia in 13/17 patients, and absence of ischemia in 15/16 patients. Conclusions: The use of 24-h tonometry after meals in patients suspected of gastrointestinal ischemia seems feasible, with promising accuracy for the detection of ischemia.
KW - Carbon dioxide
KW - Chronic mesenteric ischemia
KW - Chronic splanchnic syndrome
KW - Gastric tonometry
KW - Small bowel tonometry
KW - Splanchnic stenosis
UR - http://www.scopus.com/inward/record.url?scp=37249009167&partnerID=8YFLogxK
U2 - 10.1007/s10620-007-9833-1
DO - 10.1007/s10620-007-9833-1
M3 - Article
C2 - 17530402
AN - SCOPUS:37249009167
SN - 0163-2116
VL - 53
SP - 133
EP - 139
JO - Digestive Diseases and Sciences
JF - Digestive Diseases and Sciences
IS - 1
ER -