Ultrafast review of ambulatory EEGs with deep learning

Catarina da Silva Lourenço, Marleen C. Tjepkema-Cloostermans, Michel J.A.M. van Putten*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
23 Downloads (Pure)

Abstract

Objective: Interictal epileptiform discharges (IED) are hallmark biomarkers of epilepsy which are typically detected through visual analysis. Deep learning has shown potential in automating IED detection, which could reduce the burden of visual analysis in clinical practice. This is particularly relevant for ambulatory electroencephalograms (EEGs), as these entail longer review times. Methods: We applied a previously trained neural network to an independent dataset of 100 ambulatory EEGs (average duration 20.6 h). From these, 42 EEGs contained IEDs, 25 were abnormal without IEDs and 33 were normal. The algorithm flagged 2 second epochs that it considered IEDs. The EEGs were provided to an expert, who used NeuroCenter EEG to review the recordings. The expert concluded if each recording contained IEDs, and was timed during the process. Results: The conclusion of the reviewer was the same as the EEG report in 97% of the recordings. Three EEGs contained IEDs that were not detected based on the flagged epochs. Review time for the 100 EEGs was approximately 4 h, with half of the recordings taking <2 minutes to review. Conclusions: Our network can be used to reduce time spent on visual analysis in the clinic by 50–75 times with high reliability. Significance: Given the large time reduction potential and high success rate, this algorithm can be used in the clinic to aid in visual analysis.

Original languageEnglish
Pages (from-to)43-48
Number of pages6
JournalClinical neurophysiology
Volume154
Early online date27 Jul 2023
DOIs
Publication statusPublished - Oct 2023

Keywords

  • Ambulatory EEG
  • Deep Learning
  • EEG
  • Epilepsy
  • Interictal Epileptiform Discharges
  • Time Reduction
  • UT-Hybrid-D

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