@inbook{fd2db219a16341359898a933587df10f,
title = "Ultrasound Contrast Agent Microbubble Dynamics",
abstract = "Ultrasound contrast agents are traditionally used in ultrasound-assisted organ perfusion imaging. Recently the use of coated microbubbles has been proposed for molecular imaging applications where the bubbles are covered with a layer of targeting ligands to bind specifically to their target cells. In this chapter we describe contrast agent microbubble behavior starting from the details of free bubble dynamics leading to a set of equations describing the dynamics of coated microbubbles. Experimentally, the dynamics of ultrasound contrast agent microbubbles is temporally resolved using the ultra-high speed camera Brandaris 128. The influence of a neighboring wall is investigated by combining the Brandaris camera with optical tweezers. It was observed that the presence of the wall can alter the bubble response. A detailed description of the bubble-wall interaction may therefore lead to improved molecular imaging strategies",
keywords = "METIS-263444, IR-79279",
author = "M.L.J. Overvelde and Henk Vos and {de Jong}, N. and Michel Versluis",
year = "2010",
doi = "10.1007/978-88-470-1494-7_7",
language = "Undefined",
isbn = "9788847014930",
series = "Springer Books in Biomedical Engineering",
publisher = "Springer",
pages = "79--97",
editor = "Gaio Paradossi and Paolo Pellegretti and Andrea Trucco",
booktitle = "Ultrasound Contrast Agents: Targeting and Processing Methods for Theranostics",
address = "Germany",
}