Skip to main navigation Skip to search Skip to main content

Ultrasound Contrast Agent Microbubble Dynamics

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

10 Downloads (Pure)

Abstract

Ultrasound contrast agents are traditionally used in ultrasound-assisted organ perfusion imaging. Recently the use of coated microbubbles has been proposed for molecular imaging applications where the bubbles are covered with a layer of targeting ligands to bind specifically to their target cells. In this chapter we describe contrast agent microbubble behavior starting from the details of free bubble dynamics leading to a set of equations describing the dynamics of coated microbubbles. Experimentally, the dynamics of ultrasound contrast agent microbubbles is temporally resolved using the ultra-high speed camera Brandaris 128. The influence of a neighboring wall is investigated by combining the Brandaris camera with optical tweezers. It was observed that the presence of the wall can alter the bubble response. A detailed description of the bubble-wall interaction may therefore lead to improved molecular imaging strategies
Original languageEnglish
Title of host publicationUltrasound Contrast Agents
Subtitle of host publicationTargeting and Processing Methods for Theranostics
EditorsGaio Paradossi, Paolo Pellegretti, Andrea Trucco
Place of PublicationMilano
PublisherSpringer
Pages79-97
Number of pages20
ISBN (Electronic)978-88-470-1494-7
ISBN (Print)978-88-470-1493-0
DOIs
Publication statusPublished - 2010

Publication series

NameSpringer Books in Biomedical Engineering
PublisherSpringer

Keywords

  • 2020 OA procedure

Fingerprint

Dive into the research topics of 'Ultrasound Contrast Agent Microbubble Dynamics'. Together they form a unique fingerprint.

Cite this