Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking

Anton Nikolaev, Hendrik H.G. Hansen, Leon de Jong, Eleonora Tagliabue, Bogdan Mihai Maris, Vincent Groenhuis, Françoise Jeanette Siepel, Marco Caballo, Ioannis Sechopoulos, Christoffel Leendert de Korte

Research output: Contribution to conferenceAbstractProfessional

12 Downloads (Pure)

Abstract

Fusion-based ultrasound (US)-guided biopsy in breast is challenging due to the high deformability of the tissue combined with the fact that the breast is usually differently deformed in CT, MR, and US acquisition which makes registration difficult.
With this phantom study, we demonstrate the feasibility of a fusion-based ultrasound-guided method for breast biopsy. 3D US and 3D CT data were acquired using dedicated imaging setups of a breast phantom freely hanging in prone position with lesions. The 3D breast CT set up was provided by Koning (Koning Corp., West Henrietta, NY). For US imaging, a dedicated breast scanning set up was developed consisting of a cone-shaped revolving water tank with a 152-mm-sized US transducer mounted in its wall and an aperture for needle insertion. With this setup, volumetric breast US data (0.5x0.5x0.5 mm3 voxel size) can be collected and reconstructed within 2 minutes. The position of the lesion as detected with breast CT was localized in the US data by rigid registration. After lesion localization, the tank rotates the transducer until the lesion is in the US plane. Since the lesion was visible on ultrasound, the performance of the registration was validated.
To facilitate guided biopsy, the lesion motion, induced by needle insertion, is estimated using cross-correlation-based speckle tracking and the tracked lesion visualized in the US image at an update frequency of 10 Hz.
Thus, in conclusion a fusion-based ultrasound-guided method was introduced which enables ultrasound-guided biopsy in breast that is applicable also for ultrasound occult lesions.
Original languageEnglish
Publication statusAccepted/In press - 3 Sep 2019
EventInternational Congress on Ultrasonics 2019 - Vives Campus Bruges, Bruges, Belgium
Duration: 3 Sep 20196 Sep 2019
https://kuleuvencongres.be/2019icu

Conference

ConferenceInternational Congress on Ultrasonics 2019
Abbreviated titleICU 2019
CountryBelgium
CityBruges
Period3/09/196/09/19
Internet address

Fingerprint

Breast
Biopsy
Transducers
Needles
Prone Position
Ultrasonography
Water

Keywords

  • Ultrasound guided biopsy,
  • Multimodality image fusion
  • 3D breast ultrasound
  • Lesion displacement tracking

Cite this

Nikolaev, A., Hansen, H. H. G., de Jong, L., Tagliabue, E., Maris, B. M., Groenhuis, V., ... de Korte, C. L. (Accepted/In press). Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking. Abstract from International Congress on Ultrasonics 2019, Bruges, Belgium.
Nikolaev, Anton ; Hansen, Hendrik H.G. ; de Jong, Leon ; Tagliabue, Eleonora ; Maris, Bogdan Mihai ; Groenhuis, Vincent ; Siepel, Françoise Jeanette ; Caballo, Marco ; Sechopoulos, Ioannis ; de Korte, Christoffel Leendert. / Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking. Abstract from International Congress on Ultrasonics 2019, Bruges, Belgium.
@conference{305d783694f141a5b07bb7089140f8e7,
title = "Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking",
abstract = "Fusion-based ultrasound (US)-guided biopsy in breast is challenging due to the high deformability of the tissue combined with the fact that the breast is usually differently deformed in CT, MR, and US acquisition which makes registration difficult.With this phantom study, we demonstrate the feasibility of a fusion-based ultrasound-guided method for breast biopsy. 3D US and 3D CT data were acquired using dedicated imaging setups of a breast phantom freely hanging in prone position with lesions. The 3D breast CT set up was provided by Koning (Koning Corp., West Henrietta, NY). For US imaging, a dedicated breast scanning set up was developed consisting of a cone-shaped revolving water tank with a 152-mm-sized US transducer mounted in its wall and an aperture for needle insertion. With this setup, volumetric breast US data (0.5x0.5x0.5 mm3 voxel size) can be collected and reconstructed within 2 minutes. The position of the lesion as detected with breast CT was localized in the US data by rigid registration. After lesion localization, the tank rotates the transducer until the lesion is in the US plane. Since the lesion was visible on ultrasound, the performance of the registration was validated.To facilitate guided biopsy, the lesion motion, induced by needle insertion, is estimated using cross-correlation-based speckle tracking and the tracked lesion visualized in the US image at an update frequency of 10 Hz.Thus, in conclusion a fusion-based ultrasound-guided method was introduced which enables ultrasound-guided biopsy in breast that is applicable also for ultrasound occult lesions.",
keywords = "Ultrasound guided biopsy,, Multimodality image fusion, 3D breast ultrasound, Lesion displacement tracking",
author = "Anton Nikolaev and Hansen, {Hendrik H.G.} and {de Jong}, Leon and Eleonora Tagliabue and Maris, {Bogdan Mihai} and Vincent Groenhuis and Siepel, {Fran{\cc}oise Jeanette} and Marco Caballo and Ioannis Sechopoulos and {de Korte}, {Christoffel Leendert}",
note = "It is a conference paper, 8 pages Final version to be uploaded after publication of conference proceedings; International Congress on Ultrasonics 2019, ICU 2019 ; Conference date: 03-09-2019 Through 06-09-2019",
year = "2019",
month = "9",
day = "3",
language = "English",
url = "https://kuleuvencongres.be/2019icu",

}

Nikolaev, A, Hansen, HHG, de Jong, L, Tagliabue, E, Maris, BM, Groenhuis, V, Siepel, FJ, Caballo, M, Sechopoulos, I & de Korte, CL 2019, 'Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking' International Congress on Ultrasonics 2019, Bruges, Belgium, 3/09/19 - 6/09/19, .

Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking. / Nikolaev, Anton; Hansen, Hendrik H.G.; de Jong, Leon; Tagliabue, Eleonora; Maris, Bogdan Mihai; Groenhuis, Vincent ; Siepel, Françoise Jeanette; Caballo, Marco; Sechopoulos, Ioannis; de Korte, Christoffel Leendert.

2019. Abstract from International Congress on Ultrasonics 2019, Bruges, Belgium.

Research output: Contribution to conferenceAbstractProfessional

TY - CONF

T1 - Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking

AU - Nikolaev, Anton

AU - Hansen, Hendrik H.G.

AU - de Jong, Leon

AU - Tagliabue, Eleonora

AU - Maris, Bogdan Mihai

AU - Groenhuis, Vincent

AU - Siepel, Françoise Jeanette

AU - Caballo, Marco

AU - Sechopoulos, Ioannis

AU - de Korte, Christoffel Leendert

N1 - It is a conference paper, 8 pages Final version to be uploaded after publication of conference proceedings

PY - 2019/9/3

Y1 - 2019/9/3

N2 - Fusion-based ultrasound (US)-guided biopsy in breast is challenging due to the high deformability of the tissue combined with the fact that the breast is usually differently deformed in CT, MR, and US acquisition which makes registration difficult.With this phantom study, we demonstrate the feasibility of a fusion-based ultrasound-guided method for breast biopsy. 3D US and 3D CT data were acquired using dedicated imaging setups of a breast phantom freely hanging in prone position with lesions. The 3D breast CT set up was provided by Koning (Koning Corp., West Henrietta, NY). For US imaging, a dedicated breast scanning set up was developed consisting of a cone-shaped revolving water tank with a 152-mm-sized US transducer mounted in its wall and an aperture for needle insertion. With this setup, volumetric breast US data (0.5x0.5x0.5 mm3 voxel size) can be collected and reconstructed within 2 minutes. The position of the lesion as detected with breast CT was localized in the US data by rigid registration. After lesion localization, the tank rotates the transducer until the lesion is in the US plane. Since the lesion was visible on ultrasound, the performance of the registration was validated.To facilitate guided biopsy, the lesion motion, induced by needle insertion, is estimated using cross-correlation-based speckle tracking and the tracked lesion visualized in the US image at an update frequency of 10 Hz.Thus, in conclusion a fusion-based ultrasound-guided method was introduced which enables ultrasound-guided biopsy in breast that is applicable also for ultrasound occult lesions.

AB - Fusion-based ultrasound (US)-guided biopsy in breast is challenging due to the high deformability of the tissue combined with the fact that the breast is usually differently deformed in CT, MR, and US acquisition which makes registration difficult.With this phantom study, we demonstrate the feasibility of a fusion-based ultrasound-guided method for breast biopsy. 3D US and 3D CT data were acquired using dedicated imaging setups of a breast phantom freely hanging in prone position with lesions. The 3D breast CT set up was provided by Koning (Koning Corp., West Henrietta, NY). For US imaging, a dedicated breast scanning set up was developed consisting of a cone-shaped revolving water tank with a 152-mm-sized US transducer mounted in its wall and an aperture for needle insertion. With this setup, volumetric breast US data (0.5x0.5x0.5 mm3 voxel size) can be collected and reconstructed within 2 minutes. The position of the lesion as detected with breast CT was localized in the US data by rigid registration. After lesion localization, the tank rotates the transducer until the lesion is in the US plane. Since the lesion was visible on ultrasound, the performance of the registration was validated.To facilitate guided biopsy, the lesion motion, induced by needle insertion, is estimated using cross-correlation-based speckle tracking and the tracked lesion visualized in the US image at an update frequency of 10 Hz.Thus, in conclusion a fusion-based ultrasound-guided method was introduced which enables ultrasound-guided biopsy in breast that is applicable also for ultrasound occult lesions.

KW - Ultrasound guided biopsy,

KW - Multimodality image fusion

KW - 3D breast ultrasound

KW - Lesion displacement tracking

M3 - Abstract

ER -

Nikolaev A, Hansen HHG, de Jong L, Tagliabue E, Maris BM, Groenhuis V et al. Ultrasound-guided breast biopsy of ultrasound occult lesions using multimodality image co-registration and tissue displacement tracking. 2019. Abstract from International Congress on Ultrasonics 2019, Bruges, Belgium.