Unconventional electrochemistry in nanogap transducers

S. Sarkar

Research output: ThesisPhD Thesis - Research UT, graduation UT

224 Downloads (Pure)

Abstract

In this thesis, the results obtained from a research project aimed at ultimately realizing an all-electrical DNA sequencing platform onto a single chip are presented. To this end, we chose electrochemical sensors that are well suited for miniaturization as well as integration with microelectronics. In particular, our device involves redox cycling within a nanospaced twin electrode system (or nanogap). By virtue of being electrical in nature, such miniaturized sensors are well suited for large-scale microfabrication techniques. This allows them to be well integrated with microelectronics that can be used as a cost effective bio-electronic platform and can be utilized for a variety of applications from clinical examination to environmental analysis. Redox cycling at nanogaps have already demonstrated their ability to resolve single molecules with specific signatures that can be used as labels during DNA sequencing. In this thesis, we explore the individual ingredients for such an integrated system.
Original languageEnglish
Awarding Institution
  • University of Twente
Supervisors/Advisors
  • Lemay, Serge, Supervisor
Award date2 Nov 2016
Place of PublicationEnschede
Publisher
Print ISBNs978-90-365-4241-8
DOIs
Publication statusPublished - 2 Nov 2016

Keywords

  • IR-102918
  • METIS-320560

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