Update on covered endovascular reconstruction of the aortic bifurcation

Michel M.P.J. Reijnen*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Objective: The covered endovascular reconstruction of the aortic bifurcation (CERAB) technique was introduced in 2009 in order to provide an anatomically and physiologically optimal endovascular reconstruction of the aortic bifurcation. Method: In the current review, all available evidence on this technique was summarized. Results: In vitro studies have shown a more favorable geometry of CERAB compared to kissing stents, leading to better local flow conditions. The results of CERAB are at least as good as those achieved with kissing stents in a more complex group of treated patients. The mid-term patency rates approach those of surgical reconstruction. Initial data show that the technique can also be used in combination with chimney grafts in order to preserve side branches. Conclusion: CERAB has proven to be the most optimal endovascular treatment option for aorto-iliac occlusive disease with regard to geometry and flow and is related to promising clinical outcomes. Prospective and comparative trials are necessary to elucidate the most optimal treatment algorithm for patients with aorto-iliac occlusive disease.

Original languageEnglish
JournalVascular
DOIs
Publication statusE-pub ahead of print/First online - 2 Jan 2020

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Stents
Transplants
Therapeutics
In Vitro Techniques

Keywords

  • aortic bifurcation, CERAB
  • Aortoiliac
  • covered balloon-expandable stent
  • covered endovascular reconstruction of the aortic bifurcation
  • endovascular
  • iliac artery
  • Leriche syndrome
  • occlusive disease

Cite this

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title = "Update on covered endovascular reconstruction of the aortic bifurcation",
abstract = "Objective: The covered endovascular reconstruction of the aortic bifurcation (CERAB) technique was introduced in 2009 in order to provide an anatomically and physiologically optimal endovascular reconstruction of the aortic bifurcation. Method: In the current review, all available evidence on this technique was summarized. Results: In vitro studies have shown a more favorable geometry of CERAB compared to kissing stents, leading to better local flow conditions. The results of CERAB are at least as good as those achieved with kissing stents in a more complex group of treated patients. The mid-term patency rates approach those of surgical reconstruction. Initial data show that the technique can also be used in combination with chimney grafts in order to preserve side branches. Conclusion: CERAB has proven to be the most optimal endovascular treatment option for aorto-iliac occlusive disease with regard to geometry and flow and is related to promising clinical outcomes. Prospective and comparative trials are necessary to elucidate the most optimal treatment algorithm for patients with aorto-iliac occlusive disease.",
keywords = "aortic bifurcation, CERAB, Aortoiliac, covered balloon-expandable stent, covered endovascular reconstruction of the aortic bifurcation, endovascular, iliac artery, Leriche syndrome, occlusive disease",
author = "Reijnen, {Michel M.P.J.}",
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Update on covered endovascular reconstruction of the aortic bifurcation. / Reijnen, Michel M.P.J.

In: Vascular, 02.01.2020.

Research output: Contribution to journalReview articleAcademicpeer-review

TY - JOUR

T1 - Update on covered endovascular reconstruction of the aortic bifurcation

AU - Reijnen, Michel M.P.J.

PY - 2020/1/2

Y1 - 2020/1/2

N2 - Objective: The covered endovascular reconstruction of the aortic bifurcation (CERAB) technique was introduced in 2009 in order to provide an anatomically and physiologically optimal endovascular reconstruction of the aortic bifurcation. Method: In the current review, all available evidence on this technique was summarized. Results: In vitro studies have shown a more favorable geometry of CERAB compared to kissing stents, leading to better local flow conditions. The results of CERAB are at least as good as those achieved with kissing stents in a more complex group of treated patients. The mid-term patency rates approach those of surgical reconstruction. Initial data show that the technique can also be used in combination with chimney grafts in order to preserve side branches. Conclusion: CERAB has proven to be the most optimal endovascular treatment option for aorto-iliac occlusive disease with regard to geometry and flow and is related to promising clinical outcomes. Prospective and comparative trials are necessary to elucidate the most optimal treatment algorithm for patients with aorto-iliac occlusive disease.

AB - Objective: The covered endovascular reconstruction of the aortic bifurcation (CERAB) technique was introduced in 2009 in order to provide an anatomically and physiologically optimal endovascular reconstruction of the aortic bifurcation. Method: In the current review, all available evidence on this technique was summarized. Results: In vitro studies have shown a more favorable geometry of CERAB compared to kissing stents, leading to better local flow conditions. The results of CERAB are at least as good as those achieved with kissing stents in a more complex group of treated patients. The mid-term patency rates approach those of surgical reconstruction. Initial data show that the technique can also be used in combination with chimney grafts in order to preserve side branches. Conclusion: CERAB has proven to be the most optimal endovascular treatment option for aorto-iliac occlusive disease with regard to geometry and flow and is related to promising clinical outcomes. Prospective and comparative trials are necessary to elucidate the most optimal treatment algorithm for patients with aorto-iliac occlusive disease.

KW - aortic bifurcation, CERAB

KW - Aortoiliac

KW - covered balloon-expandable stent

KW - covered endovascular reconstruction of the aortic bifurcation

KW - endovascular

KW - iliac artery

KW - Leriche syndrome

KW - occlusive disease

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