UV cross-linkable graphene/poly(trimethylene carbonate) composites for 3D printing of electrically conductive scaffolds

Sepidar Sayyar, Miina Bjorninen, Suvi Haimi, Susanna Miettinen, Kerry Gilmore, Dirk Grijpma, Gordon Wallace*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

51 Citations (Scopus)
273 Downloads (Pure)

Abstract

Conductive, flexible graphene/poly(trimethylene carbonate) (PTMC) composites were prepared. Addition of just 3 wt % graphene to PTMC oligomers functionalized with methacrylate end-groups followed by UV cross-linking resulted in more than 100% improvement in tensile strength and enhanced electrical conductivity by orders of magnitude without altering the processability of the host material. The addition of graphene also enhanced mesenchymal stem cell (MSC) attachment and proliferation. When electrical stimulation via the composite material was applied, MSC viability was not compromised, and osteogenic markers were upregulated. Using additive fabrication techniques, the material was processed into multilayer 3D scaffolds which supported MSC attachment. These conducting composites with excellent processability and compatibility with MSCs are promising biomaterials to be used as versatile platforms for biomedical applications.

Original languageEnglish
Pages (from-to)31916-31925
Number of pages10
JournalACS applied materials & interfaces
Volume8
Issue number46
Early online date10 Nov 2016
DOIs
Publication statusPublished - 23 Nov 2016

Keywords

  • Additive fabrications
  • Biomaterials
  • Graphene
  • Mesenchymal stem cells
  • PTMC

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