Value of automatic patient motion detection and correction in myocardial perfusion imaging using a CZT-based SPECT camera

Joris D. van Dijk*, Jorn A. van Dalen, Mohamed Mouden, Jan Paul Ottervanger, Siert Knollema, Cornelis H. Slump, Pieter L. Jager

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    12 Citations (Scopus)
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    Background: Correction of motion has become feasible on cadmium-zinc-telluride (CZT)-based SPECT cameras during myocardial perfusion imaging (MPI). Our aim was to quantify the motion and to determine the value of automatic correction using commercially available software.

    Methods and Results: We retrospectively included 83 consecutive patients who underwent stress-rest MPI CZT-SPECT and invasive fractional flow reserve (FFR) measurement. Eight-minute stress acquisitions were reformatted into 1.0- and 20-second bins to detect respiratory motion (RM) and patient motion (PM), respectively. RM and PM were quantified and scans were automatically corrected. Total perfusion deficit (TPD) and SPECT interpretation—normal, equivocal, or abnormal—were compared between the noncorrected and corrected scans. Scans with a changed SPECT interpretation were compared with FFR, the reference standard. Average RM was 2.5 ± 0.4 mm and maximal PM was 4.5 ± 1.3 mm. RM correction influenced the diagnostic outcomes in two patients based on TPD changes ≥7% and in nine patients based on changed visual interpretation. In only four of these patients, the changed SPECT interpretation corresponded with FFR measurements. Correction for PM did not influence the diagnostic outcomes.

    Conclusion: Respiratory motion and patient motion were small. Motion correction did not appear to improve the diagnostic outcome and, hence, the added value seems limited in MPI using CZT-based SPECT cameras.

    Original languageEnglish
    Pages (from-to)419-428
    Number of pages10
    JournalJournal of nuclear cardiology
    Issue number2
    Publication statusPublished - 1 Apr 2018


    • Cadmium-zinc-telluride (CZT)
    • Motion correction
    • Myocardial perfusion imaging (MPI)
    • Patient motion
    • Respiratory motion


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