Vascularization in Oral and Maxillofacial Tissue Engineering

Fabian Stein, Vasileios Trikalitis, Jeroen Rouwkema*, Nasim Salehi-Nik

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingChapterProfessional


    This book provides a thorough, up-to-date description of the scientific basis and concepts of tissue engineering in the oral and maxillofacial region. The opening chapters present an introduction to tissue engineering, describe the roles of biomaterials and stem cells, discuss the use of growth factors, and examine potential adverse reactions. The challenges of soft and hard tissue engineering for oral and maxillofacial reconstruction are then considered in detail. It is explained what has been achieved to date, and potential future perspectives are explored. The importance and the verification of adequate vascularization are discussed, and a further focus is the use of 3D printing, both in the planning and production of scaffolds and in the bioprinting of cells and biomaterials. Information is also included on safety, efficacy, and regulatory aspects. Tissue Engineering in Oral and Maxillofacial Surgery will be of interest to all researchers and practitioners who wish to learn more about the potential of tissue engineering to revolutionize practice in oral and maxillofacial surgery.
    Original languageEnglish
    Title of host publicationTissue Engineering in Oral and Maxillofacial Surgery
    EditorsRiitta Seppänen-Kaijansinkko
    PublisherSpringer Nature
    Number of pages26
    ISBN (Electronic)978-3-030-24517-7
    ISBN (Print)978-3-030-24516-0
    Publication statusE-pub ahead of print/First online - 3 Dec 2019


    • Vascularization
    • Tissue Engineering
    • 3D Printing
    • Spheroids
    • Bone


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