Versatile post-functionalization of the external shell of cowpea chlorotic mottle virus by using click chemistry

C.A. Hommersom, B.D. Matt, A.M. van der Ham, Jeroen Johannes Lambertus Maria Cornelissen, Nathalie Hélène Katsonis

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Abstract

We present the modification of the outer protein shell of cowpea chlorotic mottle virus (CCMV) with linear and strained alkyne groups. These functionalized protein capsids constitute valuable platforms for post-functionalization via click chemistry. After modification, the integrity of the capsid and the reversible disassembly behavior are preserved.
Original languageEnglish
Pages (from-to)4065-4069
Number of pages4
JournalOrganic & biomolecular chemistry
Volume12
Issue number24
DOIs
Publication statusPublished - 2014

Keywords

  • METIS-308340
  • IR-95070

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