Abstract
| Original language | Undefined |
|---|---|
| Pages (from-to) | 811-825 |
| Number of pages | 14 |
| Journal | Advanced drug delivery reviews |
| Volume | 64 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2012 |
Keywords
- IR-85019
- METIS-293508
Cite this
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Virus-based nanocarriers for drug delivery. / Ma, Y.; Nolte, R.J.M.; Cornelissen, Jeroen Johannes Lambertus Maria.
In: Advanced drug delivery reviews, Vol. 64, No. 9, 2012, p. 811-825.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Virus-based nanocarriers for drug delivery
AU - Ma, Y.
AU - Nolte, R.J.M.
AU - Cornelissen, Jeroen Johannes Lambertus Maria
PY - 2012
Y1 - 2012
N2 - New nanocarrier platforms based on natural biological building blocks offer great promises in revolutionalizing medicine. The usage of specific protein cage structures: virus-like particles (VLPs) for drug packaging and targetted delivery is summarized here. Versatile chemical and genetic modifications on the outer surfaces and inner cavities of VLPs facilitate the preparation of new materials that could meet the biocompatibility, solubility and high uptake efficiency requirements for drug delivery. A full evaluation on the toxicity, bio-distribution and immunology of these materials are envisaged to boost their application potentials.
AB - New nanocarrier platforms based on natural biological building blocks offer great promises in revolutionalizing medicine. The usage of specific protein cage structures: virus-like particles (VLPs) for drug packaging and targetted delivery is summarized here. Versatile chemical and genetic modifications on the outer surfaces and inner cavities of VLPs facilitate the preparation of new materials that could meet the biocompatibility, solubility and high uptake efficiency requirements for drug delivery. A full evaluation on the toxicity, bio-distribution and immunology of these materials are envisaged to boost their application potentials.
KW - IR-85019
KW - METIS-293508
U2 - 10.1016/j.addr.2012.01.005
DO - 10.1016/j.addr.2012.01.005
M3 - Article
VL - 64
SP - 811
EP - 825
JO - Advanced drug delivery reviews
JF - Advanced drug delivery reviews
SN - 0169-409X
IS - 9
ER -