TY - JOUR
T1 - What is the Place for Uricosuric Agents in Gout Management?
AU - Siddiq, Md Abu Bakar
AU - Jansen, Tim L.
AU - Rasker, Johannes J.
PY - 2022/11
Y1 - 2022/11
N2 - The auto-inflammatory rheumatic disorder gout is a worldwide problem [1]. It causes pain and loss of function when inadequately treated, leading to high costs and loss of productivity, income, and quality of life [1]. Gout is characterized by hyperuricemia and arousal of the NLRP3 (nucleotide-binding domain, leucine-rich repeat-containing proteins) inflammasome resulting in inflammatory arthritis and soft tissue rheumatism due to deposition of monosodium urate (MSU) crystals in joints and soft tissues around [2]. The clinical presentation of gout can be misleading, and other diseases can present in similar ways. In the elderly, gout is often not diagnosed as it frequently presents in the hands of elderly slim women and men [3]. The article focuses the gout management with particular attention to the uricosuric agents. Discussing anti-inflammatory medications details is our study limitation.
AB - The auto-inflammatory rheumatic disorder gout is a worldwide problem [1]. It causes pain and loss of function when inadequately treated, leading to high costs and loss of productivity, income, and quality of life [1]. Gout is characterized by hyperuricemia and arousal of the NLRP3 (nucleotide-binding domain, leucine-rich repeat-containing proteins) inflammasome resulting in inflammatory arthritis and soft tissue rheumatism due to deposition of monosodium urate (MSU) crystals in joints and soft tissues around [2]. The clinical presentation of gout can be misleading, and other diseases can present in similar ways. In the elderly, gout is often not diagnosed as it frequently presents in the hands of elderly slim women and men [3]. The article focuses the gout management with particular attention to the uricosuric agents. Discussing anti-inflammatory medications details is our study limitation.
KW - n/a OA procedure
UR - http://www.scopus.com/inward/record.url?scp=85140415322&partnerID=8YFLogxK
U2 - 10.2174/1573397118666220308160124
DO - 10.2174/1573397118666220308160124
M3 - Article
C2 - 35260069
AN - SCOPUS:85140415322
SN - 1573-3971
VL - 18
SP - 279
EP - 285
JO - Current rheumatology reviews
JF - Current rheumatology reviews
IS - 4
ER -