TY - JOUR
T1 - Whispering-gallery-mode resonator technique with microfluidic channel for permittivity measurement of liquids
AU - Gubin, Alexey I.
AU - Barannik, Alexander A.
AU - Cherpak, Nickolay T.
AU - Protsenko, Irina A.
AU - Pud, Sergey
AU - Offenhäusser, Andreas
AU - Vitusevich, Svetlana A.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Studies of biochemical liquids require precise determination of their complex permittivity. We developed a microwave characterization technique on the basis of a high-quality whispering-gallery mode (WGM) sapphire resonator with a microfluidic channel filled with the liquid under test. A novel approach allows obtaining the complex permittivity of biochemical liquids of sub-microliter/nanoliter volumes with high accuracy. The method is based on a special procedure of analysis of the interaction of electromagnetic field with liquid in a WGM microfluidic resonator and measurements of both the WGM resonance frequency shift and the change of the inverse quality factor. The approach is successfully applied to obtain the complex permittivity in the Ka-band of glucose, albumin bovine serum, lactalbumin, and cytochrome C aqueous solutions using the developed microwave technique.
AB - Studies of biochemical liquids require precise determination of their complex permittivity. We developed a microwave characterization technique on the basis of a high-quality whispering-gallery mode (WGM) sapphire resonator with a microfluidic channel filled with the liquid under test. A novel approach allows obtaining the complex permittivity of biochemical liquids of sub-microliter/nanoliter volumes with high accuracy. The method is based on a special procedure of analysis of the interaction of electromagnetic field with liquid in a WGM microfluidic resonator and measurements of both the WGM resonance frequency shift and the change of the inverse quality factor. The approach is successfully applied to obtain the complex permittivity in the Ka-band of glucose, albumin bovine serum, lactalbumin, and cytochrome C aqueous solutions using the developed microwave technique.
KW - Computer simulations
KW - Dielectric liquids
KW - Inverse problems
KW - Microfluidics
KW - Microwave measurement
KW - permittivity
UR - http://www.scopus.com/inward/record.url?scp=84957947394&partnerID=8YFLogxK
U2 - 10.1109/TMTT.2015.2423289
DO - 10.1109/TMTT.2015.2423289
M3 - Article
AN - SCOPUS:84957947394
SN - 0018-9480
VL - 63
SP - 2003
EP - 2009
JO - IEEE transactions on microwave theory and techniques
JF - IEEE transactions on microwave theory and techniques
IS - 6
M1 - 7097100
ER -